Intravitreal bevacizumab (Avastin) for the treatment of choroidal neovascularization in age-related macular degeneration: results from 118 cases.

نویسندگان

  • K C Madhusudhana
  • S R Hannan
  • C P R Williams
  • S V Goverdhan
  • C Rennie
  • A J Lotery
  • A J Luff
  • R S B Newsom
چکیده

1 Rahman I, Maino A, Cook AE, et al. Mortality following exenteration for malignant tumours of the orbit. Br J Ophthalmol 2005;89:1445–8. 2 Tyers AG. Orbital exenteration for invasive skin tumours. Eye 2006;20:1165–70. 3 Gunalp I, Gunduz K, Duruk K. Orbital exenteration: a review of 429 cases. Int Ophthalmol 1995;19:177–84. 4 Ben Simon GJ, Schwarcz RM, Douglas R, et al. Orbital exenteration: one size does not fit all. Am J Ophthalmol 2005;139:11–17. 5 Sherman RA, Hall MJ, Thomas S. Medicinal maggots: an ancient remedy for some contemporary afflictions. Annu Rev Entomol 2000;45:55–81. 6 Mumcuoglu KY, Miller J, Mumcuoglu M, et al. Destruction of bacteria in the digestive tract of the maggot of Lucilia sericata (Diptera: Calliphoridae). J Med Entomol 2001;38:161–6. 7 Kerridge A, Lappin-Scott H, Stevens JR. Antibacterial properties of larval secretions of the blowfly, Lucilia sericata. Med Vet Entomol 2005;19:333–7. 8 Horobin AJ, Shakesheff KM, Pritchard DI. Promotion of human dermal fibroblast migration, matrix remodelling and modification of fibroblast morphology within a novel 3D model by Lucilia sericata larval secretions. J Invest Dermatol 2006;126:1410–18. 9 Wolff H, Hansson C. Larval therapy – an effective method of ulcer debridement. Clin Exp Dermatol 2003;28:134–7. 10 Sherman RA. Maggot therapy for foot and leg wounds. Int J Low Extrem Wounds 2002;1:135–42.

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Testing Toxicity of Intravitreal Bevacizumab (Avastin) used for the Treatment of Choroidal Neovascularization Associated with Age-Related Macular Degeneration: A Full Field ERG Study

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 Abstract Background: Transpupillary thermotherapy is a new treatment for subfoveal choroidal neovascularization which needs further evaluation. This study was aimed to evaluate the efficacy of transpupillary thermotherapy on regression of occult subfoveal choroidal neovascularization with or without pigment epithelial detachment in patients with age-related macular degeneration. Methods: In a ...

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Photodynamic therapy combined with intravitreal bevacizumab (Avastin) in treatment of choroidal neovascularization secondary to age-related macular degeneration.

To evaluate photodynamic therapy with verteporfin combined with intravitreal bevacizumab in minimally classic and occult choroidal neovascularization secondary to age-related macular degeneration. 46 eyes of 46 patients (mean age 74.5) included in this prospective, noncomparative, interventional case series. Median follow-up was 24 weeks (12-36). Verteporfin photodynamic therapy (PDT) was follo...

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A randomised, double-masked phase III/IV study of the efficacy and safety of Avastin® (Bevacizumab) intravitreal injections compared to standard therapy in subjects with choroidal neovascularisation secondary to age-related macular degeneration: clinical trial design

BACKGROUND The management of neovascular age-related macular degeneration (nAMD) has been transformed by the introduction of agents delivered by intravitreal injection which block the action of vascular endothelial growth factor-A (anti-VEGF agents). One such agent in widespread use is bevacizumab which was initially developed for use in oncology. Most of the evidence supporting the use of beva...

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Multifocal Electroretinogram Findings after Intravitreal Bevacizumab Injection in Choroidal Neovascularization of Age-Related Macular Degeneration

PURPOSE To evaluate the changes in multifocal electroretinogram (mfERG) and optical coherence tomography (OCT) after intravitreal bevacizumab injection in the treatment of age-related macular degeneration (AMD). METHODS Twenty-one eyes with choroidal neovascularization secondary to AMD were studied before and after intravitreal bevacizumab injection for best corrected visual acuity (BCVA), OC...

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عنوان ژورنال:
  • The British journal of ophthalmology

دوره 91 12  شماره 

صفحات  -

تاریخ انتشار 2007